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TLC Pharmaceutical Standards

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ABEMACICLIB

A-253032

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Catalogue Number:	A-253032
Compound Name:	Abemaciclib Impurity 9 DiHCl
Synonyms:	(6-((5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)pyrimidin-2-yl)amino)pyridin-3-yl)methanol, hydrochloride (1:2)
CAS#:
Alternate CAS#:	1648707-16-7 (free base)
Molecular Formula:	C₂₁H₂₀F₂N₆O. 2HCl
Molecular Weight:	410.43 2*36.46

Related Product

A-253001

Abemaciclib Mesylate

Abemaciclib Mesylate

CAS No. 1231930-82-7

C₂₇H₃₂F₂N₈. CH₄O₃S

M.W. 506.61 96.10

A-253002

Abemaciclib Mesylate

Abemaciclib Impurity 1

CAS No. 1231930-33-8

C₁₁H₁₂BrFN₂

M.W. 271.13

A-253003

Abemaciclib Mesylate

Abemaciclib Impurity 2

CAS No. 1038408-36-4

C₁₁H₁₃BrN₂

M.W. 253.14

A-253004

Abemaciclib Mesylate

Abemaciclib Impurity 3

CAS No. 1231930-29-2

C₁₁H₁₃BrF₂N₂

M.W. 291.14

A-253005

Abemaciclib Mesylate

Abemaciclib Impurity 4

CAS No. 5509-65-9

C₆H₅F₂N

M.W. 129.11

A-253006

Abemaciclib Mesylate

Abemaciclib Impurity 5

CAS No. 367-24-8

C₆H₅BrFN

M.W. 190.02

A-253007

Abemaciclib Mesylate

Abemaciclib Impurity 6

CAS No. 67567-26-4

C₆H₄BrF₂N

M.W. 208.01

A-253008

Abemaciclib Mesylate

N-Nitroso Abemaciclib

C₂₇H₃₁F₂N₉O

M.W. 535.60

A-253009

Abemaciclib Mesylate

Abemaciclib-d5

CAS No. 1809251-51-1

C₂₇H₂₇D₅F₂N₈

M.W. 511.64

A-253010

Abemaciclib Mesylate

Abemaciclib Impurity 7

CAS No. 1231930-42-9

C₁₅H₁₃ClF₂N₄

M.W. 322.74

A-253011

Abemaciclib Mesylate

Abemaciclib Impurity 8

CAS No. 1627082-92-1

C₂₁H₁₈F₂N₆O

M.W. 408.41

A-253012

Abemaciclib Mesylate

Abemaciclib Impurity 9

CAS No. 1648707-16-7

C₂₁H₂₀F₂N₆O

M.W. 410.43

A-253013

Abemaciclib Mesylate

Abemaciclib Impurity 10

C₂₁H₁₈F₂N₆O

M.W. 408.41

A-253014

Abemaciclib Mesylate

Abemaciclib Impurity 11

C₂₇H₃₂F₂N₈

M.W. 506.61

A-253015

Abemaciclib Mesylate

Abemaciclib Impurity 12

C₄₂H₄₄F₄N₁₂

M.W. 792.89

A-253016

Abemaciclib Mesylate

Abemaciclib Impurity 13

C₄₆H₄₆F₄N₁₄

M.W. 870.97

A-253017

Abemaciclib Mesylate

Abemaciclib Metabolite M2 (N-Desethyl Abemaciclib)

CAS No. 1231930-57-6

C₂₅H₂₈F₂N₈

M.W. 478.55

A-253018

Abemaciclib Mesylate

Abemaciclib Metabolite M20

CAS No. 2138499-06-4

C₂₇H₃₂F₂N₈O

M.W. 522.60

A-253019

Abemaciclib Mesylate

Abemaciclib Impurity 16

CAS No. 1180132-17-5

C₁₂H₂₀N₄

M.W. 220.32

A-253020

Abemaciclib Mesylate

Abemaciclib Impurity 17

CAS No. 414881-11-1

C₁₂H₁₉N₃

M.W. 205.31

A-253021

Abemaciclib Mesylate

Abemaciclib Impurity 18

CAS No. 1528469-78-4

C₁₁H₁₃FN₂

M.W. 192.24

A-253022

Abemaciclib Mesylate

Abemaciclib Impurity 19

CAS No. 1231930-25-8

C₁₂H₁₈BrN₃

M.W. 284.20

A-253023

Abemaciclib Mesylate

Abemaciclib Impurity 20

C₁₀H₁₃F₂NO

M.W. 201.22

A-253025

Abemaciclib Mesylate

Abemaciclib N2-N-oxide

C₂₇H₃₂F₂N₈O

M.W. 522.60

A-253026

Abemaciclib Mesylate

Abemaciclib N,N-di-N-oxide

C₂₇H₃₂F₂N₈O₂

M.W. 538.60

A-253027

Abemaciclib Mesylate

Abemaciclib Impurity 21

C₂₇H₃₂F₂N₈O

M.W. 522.60

A-253028

Abemaciclib Mesylate

Abemaciclib Impurity 22

C₂₇H₃₂F₂N₈O

M.W. 522.60

A-253029

Abemaciclib Mesylate

Abemaciclib Impurity 23

C₂₇H₃₂F₂N₈O

M.W. 522.60

A-253030

Abemaciclib Mesylate

Abemaciclib Impurity 24

C₂₆H₃₀F₂N₈O

M.W. 508.58

A-253031

Abemaciclib Mesylate

Abemaciclib Impurity 25

CAS No. 2379819-71-1

C₁₈H₃₆N₄Si₂

M.W. 364.68

A-253033

Abemaciclib Mesylate

Abemaciclib Impurity 26

C₁₅H₁₄F₂N₄

M.W. 288.30

A-253034

Abemaciclib Mesylate

Abemaciclib Impurity 27 Tetrafluoroborate

CAS No. 125942-01-0

C₆H₃BrFN₂. BF₄

M.W. 202.01 86.80

A-253035

Abemaciclib Mesylate

N1-Nitroso Abemaciclib Metabolite M2 (N1-Nitroso N-Desethyl Abemaciclib)

CAS No. 3104323-43-2

C₂₅H₂₇F₂N₉O

M.W. 507.55

A-253036

Abemaciclib Mesylate

Abemaciclib Impurity 28

CAS No. 2768138-79-8

C₁₁H₁₂ClFN₂

M.W. 226.68

A-253037

Abemaciclib Mesylate

Abemaciclib Impurity 29

CAS No. 1016745-43-9

C₁₂H₁₈ClN₃

M.W. 239.75

A-253038

Abemaciclib Mesylate

Abemaciclib Impurity 30

CAS No. 2346512-66-9

C₁₁H₁₄BFN₂O₂

M.W. 236.05

A-253039

Abemaciclib Mesylate

Abemaciclib Impurity 31

CAS No. 3062616-90-1

C₂₂H₂₄F₂N₄

M.W. 382.46

A-253040

Abemaciclib Mesylate

Abemaciclib Impurity 32

C₂₆H₂₅F₃N₆

M.W. 478.52

A-253041

Abemaciclib Mesylate

Abemaciclib Impurity 33

C₁₅H₁₃ClF₂N₄O

M.W. 338.74

A-253042

Abemaciclib Mesylate

Abemaciclib Impurity 34

C₁₅H₁₃ClF₂N₄

M.W. 322.74

A-253043

Abemaciclib Mesylate

Abemaciclib Impurity 35

C₂₁H₂₆F₂N₆

M.W. 400.48

A-253044

Abemaciclib Mesylate

Abemaciclib Impurity 36

CAS No. 155-12-4

C₄H₂ClFN₂O

M.W. 148.52

A-253045

Abemaciclib Mesylate

Abemaciclib Impurity 37

CAS No. 1873299-08-1

C₂₇H₃₀F₂N₈O

M.W. 520.25

A-253046

Abemaciclib Mesylate

Abemaciclib Impurity 38

CAS No. 1275904-70-5

C₁₂H₁₈N₄O

M.W. 234.15

A-253047

Abemaciclib Mesylate

Abemaciclib Metabolite M18 Tritrifluoroacetate

C₂₅H₂₈F₂N₈O. 3C₂HF₃O₂

M.W. 494.55 3*114.02

A-253048

Abemaciclib Mesylate

Abemaciclib Impurity 40

C₂₄H₂₆F₂N₈

M.W. 464.52

A-253049

Abemaciclib Mesylate

N-Nitroso Abemaciclib Impurity 40

C₂₄H₂₅F₂N₉O

M.W. 493.52

A-253050

Abemaciclib Mesylate

Di-N-Nitroso Abemaciclib Impurity 40

C₂₄H₂₄F₂N₁₀O₂

M.W. 522.52

A-253051

Abemaciclib Mesylate

Abemaciclib Impurity 41 (M1)

C₂₇H₃₂F₂N₈O

M.W. 522.60

A-253052

Abemaciclib Mesylate

Abemaciclib Impurity 42

C₁₁H₁₂BrFN₂

M.W. 271.13

A-253053

Abemaciclib Mesylate

Abemaciclib Impurity 43

CAS No. 1178566-47-6

C₁₀H₁₆N₄

M.W. 192.27

A-253054

Abemaciclib Mesylate

N-Nitroso Abemaciclib Impurity 43

C₁₀H₁₅N₅O

M.W. 221.26

A-253055

Abemaciclib Mesylate

Abemaciclib Metabolite M2-d6 ((N1-Nitroso N-Desethyl Abemaciclib-d6)

C₂₅H₂₂D₆F₂N₈

M.W. 484.59

A-253056

Abemaciclib Mesylate

Abemaciclib Metabolite M20-d8

C₂₇H₂₄D₈F₂N₈O

M.W. 530.65

A-253057

Abemaciclib Mesylate

N1,N2-DiNitroso Abemaciclib Metabolite M2

C₂₅H₂₆F₂N₁₀O₂

M.W. 536.548

A-253058

Abemaciclib Mesylate

N1,N2-Dinitroso Abemaciclib Impurity 44

C₂₃H₂₂F₂N₁₀O₂

M.W. 508.49

A-253059

Abemaciclib Mesylate

N-Nitroso Abemaciclib Impurity 9

C₂₁H₁₉F₂N₇O₂

M.W. 439.43

A-253060

Abemaciclib Mesylate

N-Nitroso Abemaciclib N-Oxide

C₂₇H₃₁F₂N₉O₂

M.W. 551.60

A-253061

Abemaciclib Mesylate

Abemaciclib N1-N-Oxide

C₂₇H₃₂F₂N₈O

M.W. 522.60

A-253062

Abemaciclib Mesylate

N-Nitroso Abemaciclib Metabolite M2-d6 (N-Nitroso N-Desethyl Abemaciclib-d6)

C₂₅H₂₂D₆F₂N₈

M.W. 484.59

A-253063

Abemaciclib Mesylate

Abemaciclib N3-N-Oxide

C₂₇H₃₂F₂N₈O

M.W. 522.61

A-253064

Abemaciclib Mesylate

Abemaciclib Impurity 39

C₁₈H₂₂Cl₂N₄

M.W. 365.30